Eli Lilly's Obesity Drug Retratrutide Shows 20.8%–22.6% Weight Loss in Phase 3 Trials

According to CNBC, on July 23, Eli Lilly announced positive results from two Phase 3 clinical trials of retratrutide, a once-weekly obesity treatment. In diabetic patients, retratrutide reduced body weight by up to 20.8% at week 80, with meaningful improvements in key blood glucose markers. In adults with severe obesity and cardiovascular disease, average weight loss reached 22.6% over the same period, with significant reductions in major cardiovascular risk factors. The company adjusted its regulatory submission timeline to Q1 2027 to complete manufacturing and quality data validation. Eli Lilly shares closed up 1.97% on July 23.
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