Eli Lilly Clears Two Obesity Drug Trials, Files for Retatrutide Approval in Q1 2027

According to Eli Lilly, on Thursday the pharmaceutical company said it will file for approval of its next-generation obesity drug retatrutide in the first quarter of 2027 after the treatment succeeded in two late-stage trials. In one trial, adults with obesity and diabetes lost an average of 20.8% of body weight (approximately 50 pounds) at 80 weeks. In a second trial, adults with severe obesity and cardiovascular disease lost an average of 22.6% of body weight (approximately 55.8 pounds) at 80 weeks. The company previously planned to submit an application in 2026 but needs additional time to gather manufacturing and quality-control data required by regulators.
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