a16z Raises Over $15B To Back AI And Crypto Projects, Empowering US Innovation Leadership

In Brief

a16z has raised over $15 billion across multiple funds to invest in AI, crypto, and other transformative technologies, aiming to support high-potential entrepreneurs and maintain US leadership in global innovation.

American venture capital firm Andreessen Horowitz (a16z) announced the successful raising of over $15 billion across multiple funds, including American Dynamism $1.176 billion, Apps $1.7 billion, Bio + Health $700 million, Infrastructure $1.7 billion, Growth $6.75 billion, and other venture strategies $3 billion, representing more than 18% of all venture capital deployed in the United States in 2025. The firm frames this milestone as an opportunity to invest in technologies and founders that can shape the next century of innovation.

At the core of a16z’s philosophy is the idea of “giving everybody a shot,” a principle centered on providing individuals with the chance to pursue ambitious opportunities regardless of their background, identity, or circumstances. This approach emphasizes the creation of avenues for personal and societal advancement, where the cumulative effect of talented individuals realizing their potential benefits the broader community. The firm contrasts this with historical models of imposed equality, suggesting that opportunity—even if not perfectly distributed—is inherently valuable in driving progress.

a16z situates this vision within the context of the United States, noting that the country has historically offered unmatched pathways for social mobility and achievement, fueling what the firm describes as a transformative improvement in global human conditions over the past 250 years. From this perspective, maintaining US technological leadership is not only a national imperative but a global one, with economic, military, geopolitical, and cultural implications if the country falters in advancing next-generation technologies.

a16z Stakes Its Future On AI And Crypto, Aiming To Secure US Leadership In Global Innovation

The firm identifies AI and cryptocurrencies as foundational architectures for the future, emphasizing the need to apply these technologies across critical domains such as biology, healthcare, defense, public safety, education, and entertainment. a16z positions itself as a steward of both entrepreneurial talent and policy influence, suggesting that failure to guide technological adoption and regulation in the US could undermine the country’s global leadership in innovation.

The current technology landscape is described as intensely competitive, particularly with China, and a16z positions its mission as fostering the most promising entrepreneurs and startups capable of creating generational impact. By directing capital, mentorship, and strategic support toward high-potential ventures, the firm aims to ensure that the benefits of technological advancement accrue to the United States, its people, and allied nations. a16z concludes by expressing gratitude to its Limited Partners for their trust over the past 16 years and commits to a future of rigorous investment in transformative innovation.

Andreessen Horowitz continues to expand its portfolio in AI and cryptocurrency sector, most recently participating in LMArena’s funding round in January 2026—a platform for LLM comparison and evaluation—and joining backers of Hippocratic AI, a developer of clinical healthcare AI agents.